Can longterm depression be cured?

I know that depression can be treated with meds/ psychotherapy but is there an actual cure? Or just ways to control it?

I'm in my mid 20s and I've been depressed forever. However, I feel like it's worsening. As I get older, my life is supposed to be getting better but I feel worse and worse each day. Often I feel completely disconnected from a lot of people and the things that go on around me. As little as 5 years ago, I had a positive outlook on my life. I felt like through hard work I could possibly be someone worthwhile. I don't feel like I fit in anywhere anymore. I don't have the kind of friendships/ life I used to have and I don't know how to ignite new positive relationships at this point in my life.

I have a job, good health, a roof over my head, food to eat and I'm grateful for that. But I don't know what to do about the rest of my life including issues from the past that haunt me everyday. I don't know if my depression is genetic, from my life experiences or a combination of both but I want some relief. Can anyone relate to this? And have you actually gotten a "cure"?

Thanks.

Update:

Thank you Emma-Jayne B. You make me feel like there is some hope.

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