Verified answer

Are you going to a hotel from Penn Station?

Most hotels will send a shuttle to pick you up from LaGuardia Airport.

It will be included in your hotel rate or an additional charge.

If no hotel and you are going to the Javits Center for example and want to get to NY Penn Station so you can walk the rest of the way, you could take the Q33 bus (Central, US Airways and Delta terminals) to the 74th/Roosevelt Station then take the E line (Blue) to New York Penn Station.

Q33: http://www.mta.info/busco/schedules/q033cur.pdf (PDF)

E: http://www.mta.info/nyct/service/eline.htm

Advisory: http://tripplanner.mta.info/NewTP/serviceAdvisorie...

Safe travels and enjoy the city.

Source(s):

http://411newyork.org/guide/2008/01/27/new-york-ar... (NY Hotels w/ Shuttle Service)

http://411newyork.org/guide/2007/05/25/laguardia-a... (LGA Shuttles)

http://411newyork.org/guide/2008/04/27/penn-statio... (NY Penn to Javits)

http://411newyork.org/guide/2007/05/09/irving-plaz... (NY Penn to Irving Plaza)

Here's how to get from LGA to Penn Station.

Step 1: purchase a $4.50 MetroCard from any Hudson News stand at the airport and take the Q33 bus from the Main Terminal to the 74th Street/Roosevelt Avenue subway station. If you're coming from the Marine Air Terminal, please take the Q47 bus to the 74th Street/Roosevelt Avenue subway station.

Step 2: at the 74th Street/Roosevelt Avenue subway station, transfer to the "E" subway line (Blue Line on the subway map). Take the Manhattan-bound (westbound) train from Roosevelt Avenue to 34th Street-Penn Station.

I hope this information is very helpful.

Good luck

Native New Yorker

Take the m60 shuttle to Astoria Blvd. Take the N train downtown and get off at 34th st (Herald Square). Get off, exit, left onto 7th ave, right onto W 33rd st, and you will arrive at Penn Station.