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Malignant pleural mesothelioma is a lethal particularly strong for cancer, the incidence is rising in the world. Due to its in vivo anatomical position, the tumor growth can be extruded and located in the center of the chest lung anatomical structure shift, including the heart and large airway. Notably tumor growth expansion can press the diaphragm, thereby allowing the respiratory dynamics is restricted.

Malignant pleural mesothelioma is the main etiological factors for asbestos exposure, many years ago when has yet to recognize the asbestos dangers, many engaged in transport, mining and insulation industry people work through exposure to asbestos fibers and asbestos, but not only the direct contact of men and women, reported by touching the overalls indirect exposure to relatives asbestos families also occurred in malignant pleural mesothelioma.

Typical time need 20 to 40 years before presentation, malignant pleural mesothelioma with a long latency.

The global incidence of approximately 10000 per year to 15000 patients. The disease incidence in the United States may have reached the peak, the main reason is that the United States in the early 70's on the asbestos ban, but in Europe, to reduce exposure to asbestos efforts should lag behind 10 years, start all cleaning and destruction of asbestos goods work is too late, therefore, incidence rate in 2010 in Europe reached a peak.

Almost all patients in the initial diagnosis of pleural mesothelioma has some cancer symptoms - usually serious shortage of breath, pain, weight loss and fatigue. Most of the patients symptoms occur in general more suddenly, and gradually deteriorated until the patient be completely bedridden and loss of the ability of activities of daily living. Need to emphasize mesothelioma symptoms are most severe pain, many nerve endings in the pleura, due to tumor growth, to be hardly worthy of belief degree of pain, pain can be intense to make patients wake up from sleep. In addition, because the tumor is located in the lung tumor extrusion or compression of the pulmonary, limiting diaphragmatic movement - the patients cannot breathe correctly.

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