Why can't my computer open exe files?

I recently got hacked and my antivirus removed heaps of infected files, however I think some of them may have been important system files.

I can now only open exe files by running as admin, but if I click on the shortcut the "Choose which program you want to open this file with" dialog comes up.

One of the files my antivirus removed (I believe permanently) is MSDERUN.exe.

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